FAQS

OBTAINING A KIT AND MAILING YOUR SAMPLE

Q: How do I order Gluten ID Testing?

A: You can order a Gluten ID test kit on line through our SHOP or obtain your kit from one of our physician partners: Huebner Family Medicine or O3 PLUS, LLC

 

Q; Is this a blood test?

A: No, a blood sample is not necessary for Gluten ID testing. Instead, cheek cells collected from inside your mouth are used to obtain a DNA sample.

 

Q: How many swabs are in the cheek cell sample kit?

A: Our kits contain two swabs in transport tubes and instructions for how to collect the cheek cells from inside both sides of your mouth.

 

Q: Does it matter when, or what, I have eaten before the test?

A: No, you do not have to change your diet for the Gluten ID test and you can eat any time before or after. Just don’t eat while you are collecting the cheek cell samples!

 

Q: Does it matter what time of day I collect my cheek swab samples?

A: Time of day does not impact Gluten ID testing because this is a DNA based test and your DNA does not change.

 

Q: Do I need to send my samples right after I have collected them?

A: Samples should be mailed within 24 hours of collection.

 

Q: Does the sample need to be refrigerated?

A: Collected samples in transport tubes can be kept and mailed at room temperature, but should not be exposed to heat.

 

Q: How do I mail the sample?

A: A prepaid USPS mailing envelope is included in every kit. Simply place your swab tubes back in the Gluten ID kit and put them in a United States Postal Service Collection Box.

NOTE: FedEx and UPS will not deliver USPS samples so do not drop off your kit with either of these carriers.

RECEIVING AND UNDERTANDING YOUR RESULTS

Q: How long does the testing take?

A: Results should be ready within 10-12 days.

 

Q: What laboratory is performing the test?

A: Testing is performed in one of LabCorp’s CAP/CLIA certified laboratories.

 

Q: How will I receive my results?

A: Results are sent via email to you and/or your doctor via the email address you provided when registering your kit.

 

Q: What if my sample doesn’t work the first time?

A: Approximately 10% of samples do not yield DNA of sufficient quality/quantity for testing. In these cases a new kit is provided free of charge. If a second sample fails, you will receive a refund.

WHAT IF I HAVE POSITIVE RESULTS

Q: What does it mean if my results are positive?

A: Positive results mean you have inherited DQ2 and/or DQ8 genes from one or both parents and can potentially transmit them to future generations.

 

Q: Do positive results mean I have celiac disease?

A: Having DQ2 and/or DQ8 genes is not diagnostic of celiac disease. However, these findings indicate your immune system has the capability to recognize gluten proteins and mount an abnormal immune response against your own tissue.

 

Q: How will I know if my immune system is attacking my me?

A: You will have classic GI related symptoms, and/or atypical systemic symptoms after eating gluten containing foods. The Signs

 

Q: If I am symptomatic, should I give up eating gluten immediately after positive test results?

A:  If a symptomatic individual on a gluten containing diet tests positive for celiac-associated genes, the best confirmatory test is tissue transglutanimase (tTG) antibody testing. However, this test will only be positive if adequate gluten has been consumed prior to testing. If your doctor wants you to have your blood tested for tTG antibodies do not go on a gluten-free diet until after your antibodies are tested.

Q: How do I obtain tissue transglutanimase (tTG) testing?

A: Your doctor will order tissue transglutanimase (tTG) testing to confirm your diagnosis.

WHAT IF I HAVE NEGATIVE RESULTS

Q: What does it mean if my results are NEGATIVE/Non-Celiac genetics?

A: NEGATIVE results mean you have not inherited the celiac-associated genes DQ2 or DQ8 and you have < 1% chance of developing full blown celiac disease of the small bowel. If you are the first degree family member of an individual with celiac disease, you can discontinue tTG screening  and small bowel biopsies.

 

Q: What if my results are negative but I still have GI symptoms and feel terrible after eating gluten containing food?

A:  You may be suffering from a gluten allergy or non-celiac gluten intolerance. Both of these conditions can produce symptoms similar to celiac associated gluten intolerance, but because you do not carry the dq2 or dq8 genes youare at less than < 1% risk of developing celiac disease. If you are still searching for the root cause of your problem you can learn more about non-celiac gluten intolerance at BeyondCeliac.org

 

Q: If my Gluten ID results are negative but I am symptomatic after consuming gluten, what should I do next to look for the root cause of my problem?

A: Other genes besides DQ2 and DQ8 may affect your immune system’s tolerance for gluten as well as non-genetic environmental factors. In addition, you could be suffering from an allergic reaction to gluten. Seeking a second opinion from a functional or integrative medicine doctor is a good way to explore what may be causing your symptoms. You may also want to consult with an allergist.

HOW DOES GLUTEN ID DIFFER FROM OTHER GENETIC TESTS?

Q: I recently did at home DNA testing to learn about my health and ancestry. My results were positive for one of the celiac DNA markers. How can Gluten ID help me learn more about my risk for developing celiac disease?

A:  Gluten ID covers all of the celiac-associated DNA markers which include HLA-DQ2.2, DQ8, DQ2.5, and DQ7. The personal genetic services tests may not cover all these markers. As you have already tested positive for one of the markers, you are at some level of risk (low, moderated, elevated) for development of celiac disease. Gluten ID looks more deeply at your celiac genetics and reports your results as a spectrum of risk instead of giving you binary positive/negative results.

Other benefits of Gluten ID testing include:

  • A reporting format designed to share with your doctor and become part of your medical record.
  • Actionable next steps including follow up testing and dietary gluten recommendations.